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Acid Ceramidase-IN-1
CAS No. 2415225-30-6
Acid Ceramidase-IN-1( —— )
Catalog No. M35177 CAS No. 2415225-30-6
Acid Ceramidase-IN-1 is a highly effective, orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1) with an IC50 of 0.166 μM and exhibits exceptional brain penetration capabilities in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 163 | In Stock |
|
| 5MG | 250 | In Stock |
|
| 10MG | 398 | In Stock |
|
| 25MG | 799 | In Stock |
|
| 50MG | 1279 | In Stock |
|
| 100MG | 1917 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAcid Ceramidase-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionAcid Ceramidase-IN-1 is a highly effective, orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1) with an IC50 of 0.166 μM and exhibits exceptional brain penetration capabilities in mice.
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DescriptionAcid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2415225-30-6
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Formula Weight331.41
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Molecular FormulaC18H25N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (150.87 mM; Ultrasonic (<60°C)
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SMILESCC(C)CNC(=O)n1c2ccc(cc2oc1=O)C1CCN(C)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664. ?
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